Talent x Opportunity Accelerator


Technology and culture are two of America’s enduring exports. We’ve nearly perfected the art, science, and business of scaling technological breakthroughs, but the ecosystem for cultural breakthroughs is much less developed. The Talent x Opportunity Initiative (TxO) is a step in that direction: a system that discovers and supports cultural geniuses who have the talent, drive and ideas to build breakthrough companies, but lack the networks and resources to do so. TxO is designed to help these entrepreneurs build durable, successful companies around their cultural innovations.
When we speak with founders building around a cultural insight, they often complain about how sparse the ecosystem is to support them, with spotty access to capital and mentorship, a lack of systematic training, and a much less developed set of company building blocks.
Our goal with the TxO Initiative is to help emerging cultural geniuses by providing them access to a new system of funding, training, and ongoing mentorship that will help these entrepreneurs build durable, successful companies.
Highlights:
- A 16-week training and mentorship accelerator program with a mix of in-person and online curriculum curated for culture-driven startups.
- $175,000 investment for founders through a Donor Advised Fund managed by the Tides Foundation.
- TxO Mentor Community: Vetted industry and subject matter experts, along with TxO alumni, who collaborate with founders at every step of their company-building journey to provide the networks and knowledge needed to scale ideas into global businesses.
- TxO Partners: Organizations who contribute bespoke products, services, and expertise to TxO companies.
Details for Fall 2025 Cycle
Thank you for your interest!
Applications for Talent x Opportunity are currently closed.
Stay tuned and follow @a16zTxO as we prepare to reopen applications in the summer for our next cohort.
Andreessen Horowitz (aka a16z) is a venture capital firm that backs bold entrepreneurs building the future through technology. We are stage agnostic. We invest in seed to venture to growth-stage technology companies, across AI, bio + healthcare, consumer, crypto, enterprise, fintech, games, infrastructure, and companies building toward American dynamism. a16z has $45B in committed capital across multiple funds.
Respect for the entrepreneur and the company-building process defines a16z. We know what it’s like to be in the founder’s shoes. General partners lead the firm, many of whom are former founders/operators, CEOs, or CTOs of successful technology companies, and have domain expertise ranging from data to artificial intelligence, biology to crypto, distributed systems to security, and marketplaces to financial services.
We aim to connect entrepreneurs, investors, executives, engineers, academics, industry experts, cultural geniuses, and others in the technology ecosystem. We have built a network of experts, including technical and executive talent; marketing and communications resources; Fortune 500/Global 2000 companies; cultural leaders and influencers; as well as other technology decision makers and key opinion leaders. Our network reflects a16z’s commitment to helping our portfolio companies grow their businesses, and our operating teams provide entrepreneurs with access to expertise and insights across the entire spectrum of company-building.

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